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Nicotinamide-induced Mitophagy: EVENT MEDIATED BY HIGH NAD(+)/NADH RATIO AND SIRT1 PROTEIN ACTIVATION
Active autophagy coupled with rapid mitochondrial fusion and fission constitutes an important mitochondrial quality control mechanism and is critical to cellular health. In our previous studies, we found that exposure of cells to nicotinamide causes a decrease in mitochondrial content and an increas...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Biochemistry and Molecular Biology
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3365962/ https://ncbi.nlm.nih.gov/pubmed/22493485 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.363747 |
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