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Critical role of c-jun N-terminal protein kinase in promoting mitochondrial dysfunction and acute liver injury
The mechanism by which c-Jun N-terminal protein kinase (JNK) promotes tissue injury is poorly understood. Thus we aimed at studying the roles of JNK and its phospho-target proteins in mouse models of acute liver injury. Young male mice were exposed to a single dose of CCl(4) (50 mg/kg, IP) and eutha...
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Publicado no: | Redox Biol |
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Main Authors: | , , , , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
Elsevier
2015
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4625008/ https://ncbi.nlm.nih.gov/pubmed/26491845 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.redox.2015.09.040 |
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