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Silencing of X-Linked MicroRNAs by Meiotic Sex Chromosome Inactivation

During the pachytene stage of meiosis in male mammals, the X and Y chromosomes are transcriptionally silenced by Meiotic Sex Chromosome Inactivation (MSCI). MSCI is conserved in therian mammals and is essential for normal male fertility. Transcriptomics approaches have demonstrated that in mice, mos...

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Bibliografiske detaljer
Udgivet i:PLoS Genet
Main Authors: Royo, Hélène, Seitz, Hervé, ElInati, Elias, Peters, Antoine H. F. M., Stadler, Michael B., Turner, James M. A.
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2015
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4624941/
https://ncbi.nlm.nih.gov/pubmed/26509798
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1005461
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