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Silencing of X-Linked MicroRNAs by Meiotic Sex Chromosome Inactivation

During the pachytene stage of meiosis in male mammals, the X and Y chromosomes are transcriptionally silenced by Meiotic Sex Chromosome Inactivation (MSCI). MSCI is conserved in therian mammals and is essential for normal male fertility. Transcriptomics approaches have demonstrated that in mice, mos...

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Détails bibliographiques
Publié dans:PLoS Genet
Auteurs principaux: Royo, Hélène, Seitz, Hervé, ElInati, Elias, Peters, Antoine H. F. M., Stadler, Michael B., Turner, James M. A.
Format: Artigo
Langue:Inglês
Publié: Public Library of Science 2015
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4624941/
https://ncbi.nlm.nih.gov/pubmed/26509798
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1005461
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