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FK506-binding protein 5 inhibits proliferation and stimulates apoptosis of glioma cells

INTRODUCTION: FK506-binding protein 5 (FKBP5) is reported to act as a scaffolding protein for Akt to promote the dephosphorylation of AKT Ser473 and suppress pancreatic cancer growth. However, other studies have shown that FKBP5 promotes tumor growth and chemoresistance through regulating NF-κB sign...

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Dettagli Bibliografici
Pubblicato in:Arch Med Sci
Autori principali: Yang, Hui, Zhang, Qing-Xiu, Pei, Dong-Sheng, Xu, Feng, Li, Yong, Yu, Ru-Tong
Natura: Artigo
Lingua:Inglês
Pubblicazione: Termedia Publishing House 2015
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4624752/
https://ncbi.nlm.nih.gov/pubmed/26528353
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.5114/aoms.2015.54864
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