FK506-binding protein 5 inhibits proliferation and stimulates apoptosis of glioma cells

INTRODUCTION: FK506-binding protein 5 (FKBP5) is reported to act as a scaffolding protein for Akt to promote the dephosphorylation of AKT Ser473 and suppress pancreatic cancer growth. However, other studies have shown that FKBP5 promotes tumor growth and chemoresistance through regulating NF-κB sign...

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Bibliographic Details
Published in:Arch Med Sci
Main Authors: Yang, Hui, Zhang, Qing-Xiu, Pei, Dong-Sheng, Xu, Feng, Li, Yong, Yu, Ru-Tong
Format: Artigo
Language:Inglês
Published: Termedia Publishing House 2015
Subjects:
Basic Research
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4624752/
https://ncbi.nlm.nih.gov/pubmed/26528353
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.5114/aoms.2015.54864
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