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T cells expressing CD123 chimeric antigen receptors for treatment of acute myeloid leukemia

PURPOSE OF REVIEW: The purpose of this article is to discuss the rationale of targeting CD123 using chimeric antigen receptor (CAR) T cells for the treatment of leukemia. RECENT FINDINGS: CD123 is a leukemia associated antigen that expresses at high levels in leukemic stem cells and leukemic blasts...

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Foilsithe in:Curr Opin Hematol
Main Authors: Mardiros, Armen, Forman, Stephen J., Budde, Lihua E
Formáid: Artigo
Teanga:Inglês
Foilsithe: 2015
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4624420/
https://ncbi.nlm.nih.gov/pubmed/26457961
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/MOH.0000000000000190
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