Increased Energy Demand during Adrenergic Receptor Stimulation Contributes to Ca(2+) Wave Generation

While β-adrenergic receptor (β-AR) stimulation ensures adequate cardiac output during stress, it can also trigger life-threatening cardiac arrhythmias. We have previously shown that proarrhythmic Ca(2+) waves during β-AR stimulation temporally coincide with augmentation of reactive oxygen species (R...

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Udgivet i:Biophys J
Main Authors: Bovo, Elisa, Mazurek, Stefan R., de Tombe, Pieter P., Zima, Aleksey V.
Format: Artigo
Sprog:Inglês
Udgivet: The Biophysical Society 2015
Fag:
Cell Biophysics
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4624344/
https://ncbi.nlm.nih.gov/pubmed/26488649
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2015.09.002
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