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Disorder-to-Order Transition of an Active-Site Loop Mediates the Allosteric Activation of Sortase A

Intrinsically disordered proteins and intrinsically disordered regions are implicated in many biological functions and associated with many diseases, but their conformational characterizations are challenging. The disordered β6/β7 loop of Staphylococcus aureus sortase A is involved in the binding of...

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Publicat a:Biophys J
Autors principals: Pang, Xiaodong, Zhou, Huan-Xiang
Format: Artigo
Idioma:Inglês
Publicat: The Biophysical Society 2015
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4624160/
https://ncbi.nlm.nih.gov/pubmed/26488662
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2015.08.039
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