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Expression kinetics of nucleoside-modified mRNA delivered in lipid nanoparticles to mice by various routes
In recent years, in vitro transcribed messenger RNA (mRNA) has emerged as a potential therapeutic platform. To fulfill its promise, effective delivery of mRNA to specific cell types and tissues needs to be achieved. Lipid nanoparticles (LNPs) are efficient carriers for short-interfering RNAs and hav...
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| Publicado no: | J Control Release |
|---|---|
| Main Authors: | , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4624045/ https://ncbi.nlm.nih.gov/pubmed/26264835 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jconrel.2015.08.007 |
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