Liposomal doxorubicin extravasation controlled by phenotype-specific transport properties of tumor microenvironment and vascular barrier

Although nanotherapeutics can be advantageous over free chemotherapy, the benefits of drug vectors can vary from patient to patient based on differences in tumor microenvironments. Although systemic pharmacokinetics (PK) of drugs is considered as the major determinant of its efficacy in clinics, rec...

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Bibliografische gegevens
Gepubliceerd in:J Control Release
Hoofdauteurs: Yokoi, Kenji, Chan, Diana, Kojic, Milos, Milosevic, Miljan, Engler, David, Matsunami, Rise, Tanei, Tomonori, Saito, Yuki, Ferrari, Mauro, Ziemys, Arturas
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2015
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Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4623952/
https://ncbi.nlm.nih.gov/pubmed/26409121
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jconrel.2015.09.044
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