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Liposomal doxorubicin extravasation controlled by phenotype-specific transport properties of tumor microenvironment and vascular barrier

Although nanotherapeutics can be advantageous over free chemotherapy, the benefits of drug vectors can vary from patient to patient based on differences in tumor microenvironments. Although systemic pharmacokinetics (PK) of drugs is considered as the major determinant of its efficacy in clinics, rec...

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Podrobná bibliografie
Vydáno v:J Control Release
Hlavní autoři: Yokoi, Kenji, Chan, Diana, Kojic, Milos, Milosevic, Miljan, Engler, David, Matsunami, Rise, Tanei, Tomonori, Saito, Yuki, Ferrari, Mauro, Ziemys, Arturas
Médium: Artigo
Jazyk:Inglês
Vydáno: 2015
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4623952/
https://ncbi.nlm.nih.gov/pubmed/26409121
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jconrel.2015.09.044
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