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Liposomal doxorubicin extravasation controlled by phenotype-specific transport properties of tumor microenvironment and vascular barrier

Although nanotherapeutics can be advantageous over free chemotherapy, the benefits of drug vectors can vary from patient to patient based on differences in tumor microenvironments. Although systemic pharmacokinetics (PK) of drugs is considered as the major determinant of its efficacy in clinics, rec...

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Detalhes bibliográficos
Publicado no:J Control Release
Main Authors: Yokoi, Kenji, Chan, Diana, Kojic, Milos, Milosevic, Miljan, Engler, David, Matsunami, Rise, Tanei, Tomonori, Saito, Yuki, Ferrari, Mauro, Ziemys, Arturas
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4623952/
https://ncbi.nlm.nih.gov/pubmed/26409121
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jconrel.2015.09.044
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