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A feedback regulatory loop involving p53/miR-200 and growth hormone endocrine axis controls embryo size of zebrafish
In vertebrates, growth hormone/insulin-like growth factor (GH/IGF) axis signaling plays a critical role in regulating somatic growth. Understanding the direct upstream regulators of GH/IGF axis remains a major challenge. Our studies of the zebrafish reveal that the conserved miR-200 family members a...
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| Veröffentlicht in: | Sci Rep |
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| Hauptverfasser: | , , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Nature Publishing Group
2015
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4623745/ https://ncbi.nlm.nih.gov/pubmed/26507500 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep15906 |
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