Cigarette smoking reduces DNA methylation levels at multiple genomic loci but the effect is partially reversible upon cessation

Smoking is a major risk factor in many diseases. Genome wide association studies have linked genes for nicotine dependence and smoking behavior to increased risk of cardiovascular, pulmonary, and malignant diseases. We conducted an epigenome wide association study in peripheral-blood DNA in 464 indi...

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Detalhes bibliográficos
Publicado no:Epigenetics
Main Authors: Tsaprouni, Loukia G, Yang, Tsun-Po, Bell, Jordana, Dick, Katherine J, Kanoni, Stavroula, Nisbet, James, Viñuela, Ana, Grundberg, Elin, Nelson, Christopher P, Meduri, Eshwar, Buil, Alfonso, Cambien, Francois, Hengstenberg, Christian, Erdmann, Jeanette, Schunkert, Heribert, Goodall, Alison H, Ouwehand, Willem H, Dermitzakis, Emmanouil, Spector, Tim D, Samani, Nilesh J, Deloukas, Panos
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2014
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4623553/
https://ncbi.nlm.nih.gov/pubmed/25424692
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/15592294.2014.969637
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