Comprehensive Exploration of the Effects of miRNA SNPs on Monocyte Gene Expression

We aimed to assess whether pri-miRNA SNPs (miSNPs) could influence monocyte gene expression, either through marginal association or by interacting with polymorphisms located in 3'UTR regions (3utrSNPs). We then conducted a genome-wide search for marginal miSNPs effects and pairwise miSNPs × 3ut...

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Hlavní autoři: Greliche, Nicolas, Zeller, Tanja, Wild, Philipp S., Rotival, Maxime, Schillert, Arne, Ziegler, Andreas, Deloukas, Panos, Erdmann, Jeanette, Hengstenberg, Christian, Ouwehand, Willem H., Samani, Nilesh J., Schunkert, Heribert, Munzel, Thomas, Lackner, Karl J., Cambien, François, Goodall, Alison H., Tiret, Laurence, Blankenberg, Stefan, Trégouët, David-Alexandre
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2012
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Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3448685/
https://ncbi.nlm.nih.gov/pubmed/23029284
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0045863
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