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Comprehensive Exploration of the Effects of miRNA SNPs on Monocyte Gene Expression

We aimed to assess whether pri-miRNA SNPs (miSNPs) could influence monocyte gene expression, either through marginal association or by interacting with polymorphisms located in 3'UTR regions (3utrSNPs). We then conducted a genome-wide search for marginal miSNPs effects and pairwise miSNPs × 3ut...

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Bibliografiske detaljer
Main Authors: Greliche, Nicolas, Zeller, Tanja, Wild, Philipp S., Rotival, Maxime, Schillert, Arne, Ziegler, Andreas, Deloukas, Panos, Erdmann, Jeanette, Hengstenberg, Christian, Ouwehand, Willem H., Samani, Nilesh J., Schunkert, Heribert, Munzel, Thomas, Lackner, Karl J., Cambien, François, Goodall, Alison H., Tiret, Laurence, Blankenberg, Stefan, Trégouët, David-Alexandre
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2012
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3448685/
https://ncbi.nlm.nih.gov/pubmed/23029284
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0045863
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