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Choroidal neovascularization is inhibited via an intraocular decrease of inflammatory cells in mice lacking complement component C3

In early age-related macular degeneration (AMD), complement component C3 can be observed in drusen, which is the accumulation of material beneath the retinal pigment epithelium. The complement pathways, via the activation of C3, can upregulate the expression of cytokines and their receptors and the...

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Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Sci Rep
Egile Nagusiak: Tan, Xue, Fujiu, Katsuhito, Manabe, Ichiro, Nishida, Junko, Yamagishi, Reiko, Nagai, Ryozo, Yanagi, Yasuo
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Nature Publishing Group 2015
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4623476/
https://ncbi.nlm.nih.gov/pubmed/26507897
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep15702
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