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Choroidal neovascularization is inhibited via an intraocular decrease of inflammatory cells in mice lacking complement component C3
In early age-related macular degeneration (AMD), complement component C3 can be observed in drusen, which is the accumulation of material beneath the retinal pigment epithelium. The complement pathways, via the activation of C3, can upregulate the expression of cytokines and their receptors and the...
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| Publicado no: | Sci Rep |
|---|---|
| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4623476/ https://ncbi.nlm.nih.gov/pubmed/26507897 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep15702 |
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