Choroidal Neovascularization Is Inhibited in Splenic-Denervated or Splenectomized Mice with a Concomitant Decrease in Intraocular Macrophage

PURPOSE: To determine the involvement of sympathetic activity in choroidal neovascularization (CNV) using laser-induced CNV in a mouse model. METHODS: We investigated changes in the proportions of intraocular lymphocytes, granulocytes, and three macrophage subtypes (Ly6C(hi), Ly6C(int), and Ly6C(lo)...

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Udgivet i:PLoS One
Main Authors: Tan, Xue, Fujiu, Katsuhito, Manabe, Ichiro, Nishida, Junko, Yamagishi, Reiko, Terashima, Yuya, Matsushima, Kouji, Kaburaki, Toshikatsu, Nagai, Ryozo, Yanagi, Yasuo
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2016
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4988653/
https://ncbi.nlm.nih.gov/pubmed/27532664
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0160985
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