ABC294640, a sphingosine kinase 2 inhibitor, enhances the antitumor effects of TRAIL in non-small cell lung cancer

Evidences suggest that tumor microenvironment may play an important role in cancer drug resistance. Sphingosine kinase 2 (SphK2) is proposed to be the key regulator of sphingolipid signaling. This study is aimed to investigate whether the combination of molecular targeting therapy using a specific i...

Description complète

Enregistré dans:
Détails bibliographiques
Publié dans:Cancer Biol Ther
Auteurs principaux: Yang, Jie, Yang, Chunxu, Zhang, Shimin, Mei, Zijie, Shi, Mingjun, Sun, Shaoxing, Shi, Liu, Wang, Zhihao, Wang, Yacheng, Li, Zhenzhen, Xie, Conghua
Format: Artigo
Langue:Inglês
Publié: Taylor & Francis 2015
Sujets:
Research Paper
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4623419/
https://ncbi.nlm.nih.gov/pubmed/26054751
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15384047.2015.1056944
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