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First human study of a chimeric anti-methamphetamine monoclonal antibody in healthy volunteers
This first-in-human study examined the safety and pharmacokinetics of ch-mAb7F9, an anti-methamphetamine monoclonal antibody, in healthy volunteers. Single, escalating doses of ch-mAb7F9 over the range of 0.2 to 20 mg/kg were administered to 42 subjects who were followed for 147 d. Safety was measur...
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| Publicat a: | MAbs |
|---|---|
| Autors principals: | , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Taylor & Francis
2014
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4623385/ https://ncbi.nlm.nih.gov/pubmed/25484042 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/19420862.2014.976431 |
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