The preclinical evaluation of the dual mTORC1/2 inhibitor INK-128 as a potential anti-colorectal cancer agent

The colorectal cancer is the leading contributor of cancer-related mortality. Mammalian target of rapamycin (mTOR), existing in 2 complexes (mTORC1/2), is frequently dysregulated and constitutively activated in colorectal cancers. It represents an important drug target. Here we found that INK-128, t...

Полное описание

Сохранить в:
Библиографические подробности
Опубликовано в: :Cancer Biol Ther
Главные авторы: Li, Chen, Cui, Jian-Feng, Chen, Min-Bin, Liu, Chao-Ying, Liu, Feng, Zhang, Qian-De, Zou, Jian, Lu, Pei-Hua
Формат: Artigo
Язык:Inglês
Опубликовано: Taylor & Francis 2015
Предметы:
Research Papers
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4623257/
https://ncbi.nlm.nih.gov/pubmed/25692620
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/15384047.2014.972274
Метки: Добавить метку
Нет меток, Требуется 1-ая метка записи!

Схожие документы