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LB100, a small molecule inhibitor of PP2A with potent chemo- and radio-sensitizing potential
Protein phosphatase 2A (PP2A) is a serine/threonine phosphatase that plays a significant role in mitotic progression and cellular responses to DNA damage. While traditionally viewed as a tumor suppressor, inhibition of PP2A has recently come to attention as a novel therapeutic means of driving senes...
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| Publicado no: | Cancer Biol Ther |
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| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Taylor & Francis
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4623051/ https://ncbi.nlm.nih.gov/pubmed/25897893 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15384047.2015.1040961 |
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