LB100, a small molecule inhibitor of PP2A with potent chemo- and radio-sensitizing potential

Protein phosphatase 2A (PP2A) is a serine/threonine phosphatase that plays a significant role in mitotic progression and cellular responses to DNA damage. While traditionally viewed as a tumor suppressor, inhibition of PP2A has recently come to attention as a novel therapeutic means of driving senes...

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Detaylı Bibliyografya
Yayımlandı:Cancer Biol Ther
Asıl Yazarlar: Hong, Christopher S, Ho, Winson, Zhang, Chao, Yang, Chunzhang, Elder, J Bradley, Zhuang, Zhengping
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Taylor & Francis 2015
Konular:
Review
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4623051/
https://ncbi.nlm.nih.gov/pubmed/25897893
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15384047.2015.1040961
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