Altering TET dioxygenase levels within physiological range affects DNA methylation dynamics of HEK293 cells

The TET family of dioxygenases (TET1/2/3) can convert 5-methylcytosine (5mC) into 5-hydroxymethylcytosine (5hmC) and has been shown to be involved in active and passive DNA demethylation. Here, we demonstrate that altering TET dioxygenase levels within physiological range can affect DNA methylation...

Descripció completa

Guardat en:
Dades bibliogràfiques
Publicat a:Epigenetics
Autors principals: Grosser, Christian, Wagner, Nicholas, Grothaus, Katrin, Horsthemke, Bernhard
Format: Artigo
Idioma:Inglês
Publicat: Taylor & Francis 2015
Matèries:
Research Paper
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4622922/
https://ncbi.nlm.nih.gov/pubmed/26186463
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15592294.2015.1073879
Etiquetes: Afegir etiqueta
Sense etiquetes, Sigues el primer a etiquetar aquest registre!

Ítems similars