Epigenetic heterogeneity of developmentally important genes in human sperm: Implications for assisted reproduction outcome

The molecular basis of male infertility is poorly understood, the majority of cases remaining unsolved. The association of aberrant sperm DNA methylation patterns and compromised semen parameters suggests that disturbances in male germline epigenetic reprogramming contribute to this problem. So far...

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Détails bibliographiques
Publié dans:Epigenetics
Auteurs principaux: Kuhtz, Juliane, Schneider, Eberhard, El Hajj, Nady, Zimmermann, Lena, Fust, Olga, Linek, Bartosz, Seufert, Rudolf, Hahn, Thomas, Schorsch, Martin, Haaf, Thomas
Format: Artigo
Langue:Inglês
Publié: Taylor & Francis 2015
Sujets:
Research Papers
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4622742/
https://ncbi.nlm.nih.gov/pubmed/25625849
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/15592294.2014.988063
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