Broad DNA methylation changes of spermatogenesis, inflammation and immune response-related genes in a subgroup of sperm samples for assisted reproduction

Aberrant sperm DNA methylation patterns, mainly in imprinted genes, have been associated with male subfertility and oligospermia. Here, we performed a genome-wide methylation analysis in sperm samples representing a wide range of semen parameters. Sperm DNA samples of 38 males attending a fertility...

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Detalhes bibliográficos
Main Authors: Schütte, B, El Hajj, N, Kuhtz, J, Nanda, I, Gromoll, J, Hahn, T, Dittrich, M, Schorsch, M, Müller, T, Haaf, T
Formato: Artigo
Idioma:Inglês
Publicado em: BlackWell Publishing Ltd 2013
Assuntos:
Original Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4033565/
https://ncbi.nlm.nih.gov/pubmed/23996961
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.2047-2927.2013.00122.x
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