Methylation status of IGFBP-3 as a useful clinical tool for deciding on a concomitant radiotherapy

The methylation status of the IGFBP-3 gene is strongly associated with cisplatin sensitivity in patients with non-small cell lung cancer (NSCLC). In this study, we found in vitro evidence that linked the presence of an unmethylated promoter with poor response to radiation. Our data also indicate tha...

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Detalhes bibliográficos
Publicado no:Epigenetics
Main Authors: Pernía, Olga, Belda-Iniesta, Cristobal, Pulido, Veronica, Cortes-Sempere, María, Rodriguez, Carlos, Vera, Olga, Soto, Javier, Jiménez, Julia, Taus, Alvaro, Rojo, Federico, Arriola, Edurne, Rovira, Ana, Albanell, Joan, Macías, M Teresa, de Castro, Javier, Perona, Rosario, Ibañez de Caceres, Inmaculada
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2014
Assuntos:
Brief Report
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4622698/
https://ncbi.nlm.nih.gov/pubmed/25482372
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/15592294.2014.971626
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