Methylation status of IGFBP-3 as a useful clinical tool for deciding on a concomitant radiotherapy

The methylation status of the IGFBP-3 gene is strongly associated with cisplatin sensitivity in patients with non-small cell lung cancer (NSCLC). In this study, we found in vitro evidence that linked the presence of an unmethylated promoter with poor response to radiation. Our data also indicate tha...

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Kaydedildi:
Detaylı Bibliyografya
Yayımlandı:Epigenetics
Asıl Yazarlar: Pernía, Olga, Belda-Iniesta, Cristobal, Pulido, Veronica, Cortes-Sempere, María, Rodriguez, Carlos, Vera, Olga, Soto, Javier, Jiménez, Julia, Taus, Alvaro, Rojo, Federico, Arriola, Edurne, Rovira, Ana, Albanell, Joan, Macías, M Teresa, de Castro, Javier, Perona, Rosario, Ibañez de Caceres, Inmaculada
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Taylor & Francis 2014
Konular:
Brief Report
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4622698/
https://ncbi.nlm.nih.gov/pubmed/25482372
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/15592294.2014.971626
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