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ARHGEF3 controls HDACi-induced differentiation via RhoA-dependent pathways in acute myeloid leukemias
Altered expression and activity of histone deacetylases (HDACs) have been correlated with tumorigenesis. Inhibitors of HDACs (HDACi) induce acetylation of histone and non-histone proteins affecting gene expression, cell cycle progression, cell migration, terminal differentiation and cell death. Here...
Gespeichert in:
| Veröffentlicht in: | Epigenetics |
|---|---|
| Hauptverfasser: | , , , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Taylor & Francis
2015
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4622697/ https://ncbi.nlm.nih.gov/pubmed/25494542 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/15592294.2014.988035 |
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