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ARHGEF3 controls HDACi-induced differentiation via RhoA-dependent pathways in acute myeloid leukemias
Altered expression and activity of histone deacetylases (HDACs) have been correlated with tumorigenesis. Inhibitors of HDACs (HDACi) induce acetylation of histone and non-histone proteins affecting gene expression, cell cycle progression, cell migration, terminal differentiation and cell death. Here...
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| 發表在: | Epigenetics |
|---|---|
| Main Authors: | , , , , , , , |
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
Taylor & Francis
2015
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4622697/ https://ncbi.nlm.nih.gov/pubmed/25494542 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/15592294.2014.988035 |
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