ARHGEF3 controls HDACi-induced differentiation via RhoA-dependent pathways in acute myeloid leukemias

Altered expression and activity of histone deacetylases (HDACs) have been correlated with tumorigenesis. Inhibitors of HDACs (HDACi) induce acetylation of histone and non-histone proteins affecting gene expression, cell cycle progression, cell migration, terminal differentiation and cell death. Here...

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Detalhes bibliográficos
Publicado no:Epigenetics
Main Authors: D’Amato, Loredana, Dell’Aversana, Carmela, Conte, Mariarosaria, Ciotta, Alfonso, Scisciola, Lucia, Carissimo, Annamaria, Nebbioso, Angela, Altucci, Lucia
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2015
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4622697/
https://ncbi.nlm.nih.gov/pubmed/25494542
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/15592294.2014.988035
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