DNA methylation analysis of Homeobox genes implicates HOXB7 hypomethylation as risk factor for neural tube defects

Neural tube defects (NTDs) are common birth defects of complex etiology. Though family- and population-based studies have confirmed a genetic component, the responsible genes for NTDs are still largely unknown. Based on the hypothesis that folic acid prevents NTDs by stimulating methylation reaction...

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Detalhes bibliográficos
Publicado no:Epigenetics
Main Authors: Rochtus, Anne, Izzi, Benedetta, Vangeel, Elise, Louwette, Sophie, Wittevrongel, Christine, Lambrechts, Diether, Moreau, Yves, Winand, Raf, Verpoorten, Carla, Jansen, Katrien, Van Geet, Chris, Freson, Kathleen
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2015
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4622610/
https://ncbi.nlm.nih.gov/pubmed/25565354
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15592294.2014.998531
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