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Cell-Specific PEAR1 Methylation Studies Reveal a Locus that Coordinates Expression of Multiple Genes

Chromosomal interactions connect distant enhancers and promoters on the same chromosome, activating or repressing gene expression. PEAR1 encodes the Platelet-Endothelial Aggregation Receptor 1, a contact receptor involved in platelet function and megakaryocyte and endothelial cell proliferation. PEA...

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Detalhes bibliográficos
Publicado no:Int J Mol Sci
Main Authors: Izzi, Benedetta, Noro, Fabrizia, Cludts, Katrien, Freson, Kathleen, Hoylaerts, Marc F.
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5979289/
https://ncbi.nlm.nih.gov/pubmed/29614055
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms19041069
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