Nalaganje...
Monomeric IgG1 Fc molecules displaying unique Fc receptor interactions that are exploitable to treat inflammation-mediated diseases
The IgG1 Fc is a dimeric protein that mediates important antibody effector functions by interacting with Fcγ receptors (FcγRs) and the neonatal Fc receptor (FcRn). Here, we report the discovery of a monomeric IgG1 Fc (mFc) that bound to FcγRI with very high affinity, but not to FcγRIIIa, in contrast...
Shranjeno v:
| izdano v: | MAbs |
|---|---|
| Main Authors: | , , , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
Taylor & Francis
2014
|
| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4622432/ https://ncbi.nlm.nih.gov/pubmed/25517305 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/mabs.29835 |
| Oznake: |
Označite
Brez oznak, prvi označite!
|