Prolonged re-expression of the hypermethylated gene EPB41L3 using artificial transcription factors and epigenetic drugs

Epigenetic silencing of tumor suppressor genes (TSGs) is considered a significant event in the progression of cancer. For example, EPB41L3, a potential biomarker in cervical cancer, is often silenced by cancer-specific promoter methylation. Artificial transcription factors (ATFs) are unique tools to...

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Dettagli Bibliografici
Pubblicato in:Epigenetics
Autori principali: Huisman, Christian, van der Wijst, Monique GP, Falahi, Fahimeh, Overkamp, Juul, Karsten, Gellért, Terpstra, Martijn M, Kok, Klaas, van der Zee, Ate GJ, Schuuring, Ed, Wisman, G Bea A, Rots, Marianne G
Natura: Artigo
Lingua:Inglês
Pubblicazione: Taylor & Francis 2015
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Research Paper
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4622424/
https://ncbi.nlm.nih.gov/pubmed/25830725
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15592294.2015.1034415
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