Inhibition of SGK1 enhances mAR-induced apoptosis in MCF-7 breast cancer cells

Functional membrane androgen receptors (mAR) have previously been described in MCF-7 breast cancer cells. Their stimulation by specific testosterone albumin conjugates (TAC) activate rapidly non-genomic FAK/PI3K/Rac1/Cdc42 signaling, trigger actin reorganization and inhibit cell motility. PI3K stimu...

Description complète

Enregistré dans:
Détails bibliographiques
Publié dans:Cancer Biol Ther
Auteurs principaux: Liu, Guilai, Honisch, Sabina, Liu, Guoxing, Schmidt, Sebastian, Pantelakos, Stavros, Alkahtani, Saad, Toulany, Mahmoud, Lang, Florian, Stournaras, Christos
Format: Artigo
Langue:Inglês
Publié: Taylor & Francis 2014
Sujets:
Research Papers
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4622018/
https://ncbi.nlm.nih.gov/pubmed/25427201
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/15384047.2014.986982
Tags: Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!

Documents similaires