Up-regulation of Orai1 expression and store operated Ca(2+) entry following activation of membrane androgen receptors in MCF-7 breast tumor cells

BACKGROUND: Membrane androgen receptors (mAR) are functionally expressed in a variety of tumor-cells including the breast tumor-cell line MCF-7. They are specifically activated by testosterone albumin conjugates (TAC). The mAR sensitive signaling includes activation of Ras-related C3 botulinum toxin...

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Detalhes bibliográficos
Publicado no:BMC Cancer
Main Authors: Liu, Guilai, Honisch, Sabina, Liu, Guoxing, Schmidt, Sebastian, Alkahtani, Saad, AlKahtane, Abdullah A., Stournaras, Christos, Lang, Florian
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2015
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4687293/
https://ncbi.nlm.nih.gov/pubmed/26690689
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12885-015-2014-2
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