The HIV-1 protein Vpr impairs phagosome maturation by controlling microtubule-dependent trafficking

Human immunodeficiency virus type 1 (HIV-1) impairs major functions of macrophages but the molecular basis for this defect remains poorly characterized. Here, we show that macrophages infected with HIV-1 were unable to respond efficiently to phagocytic triggers and to clear bacteria. The maturation...

Full beskrivning

Sparad:
Bibliografiska uppgifter
I publikationen:J Cell Biol
Huvudupphovsmän: Dumas, Audrey, Lê-Bury, Gabrielle, Marie-Anaïs, Florence, Herit, Floriane, Mazzolini, Julie, Guilbert, Thomas, Bourdoncle, Pierre, Russell, David G., Benichou, Serge, Zahraoui, Ahmed, Niedergang, Florence
Materialtyp: Artigo
Språk:Inglês
Publicerad: The Rockefeller University Press 2015
Ämnen:
Research Articles
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4621833/
https://ncbi.nlm.nih.gov/pubmed/26504171
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201503124
Taggar: Lägg till en tagg
Inga taggar, Lägg till första taggen!

Liknande verk