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Palladin Mediates Stiffness-Induced Fibroblast Activation in the Tumor Microenvironment

Mechanical properties of the tumor microenvironment have emerged as key factors in tumor progression. It has been proposed that increased tissue stiffness can transform stromal fibroblasts into carcinoma-associated fibroblasts. However, it is unclear whether the three to five times increase in stiff...

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Publicat a:Biophys J
Autors principals: McLane, Joshua S., Ligon, Lee A.
Format: Artigo
Idioma:Inglês
Publicat: The Biophysical Society 2015
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4621820/
https://ncbi.nlm.nih.gov/pubmed/26200861
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2015.06.033
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