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Palladin Mediates Stiffness-Induced Fibroblast Activation in the Tumor Microenvironment

Mechanical properties of the tumor microenvironment have emerged as key factors in tumor progression. It has been proposed that increased tissue stiffness can transform stromal fibroblasts into carcinoma-associated fibroblasts. However, it is unclear whether the three to five times increase in stiff...

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Detalhes bibliográficos
Publicado no:Biophys J
Main Authors: McLane, Joshua S., Ligon, Lee A.
Formato: Artigo
Idioma:Inglês
Publicado em: The Biophysical Society 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4621820/
https://ncbi.nlm.nih.gov/pubmed/26200861
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2015.06.033
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