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Store-operated CRAC channels regulate PAR2-activated Ca(2+) signaling and cytokine production in airway epithelial cells
The G-protein coupled protease-activated receptor 2 (PAR2) plays an important role in the pathogenesis of various inflammatory and auto-immune disorders. In airway epithelial cells (AECs), stimulation of PAR2 by allergens and proteases triggers the release of a host of inflammatory mediators to regu...
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| Veröffentlicht in: | J Immunol |
|---|---|
| Hauptverfasser: | , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2015
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4621783/ https://ncbi.nlm.nih.gov/pubmed/26238490 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1500396 |
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