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DCs induce CD40-independent immunoglobulin class switching through BLyS and APRIL
Immunoglobulin (Ig) class-switch DNA recombination (CSR) is thought to be highly dependent upon engagement of CD40 on B cells by CD40 ligand on T cells. We show here that dendritic cells up-regulate BLyS and APRIL upon exposure to interferon-α, interferon-γ or CD40 ligand. In the presence of interle...
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| Publicado no: | Nat Immunol |
|---|---|
| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2002
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4621779/ https://ncbi.nlm.nih.gov/pubmed/12154359 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ni829 |
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