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An FcγRIIa Polymorphism with Decreased C-Reactive Protein Binding is Associated with Sepsis and Decreased Monocyte HLA-DR Expression in Trauma Patients
INTRODUCTION: A dysregulated immune response leading to sepsis is the most frequent cause of late post-traumatic deaths. We have found a novel anti-inflammatory pathway that is initiated by the acute phase protein, C-reactive protein (CRP), interacting with Fcγ receptor (FcγR) on monocytes. This pat...
Gorde:
| Argitaratua izan da: | J Trauma Acute Care Surg |
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| Egile Nagusiak: | , , , , , |
| Formatua: | Artigo |
| Hizkuntza: | Inglês |
| Argitaratua: |
2015
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| Gaiak: | |
| Sarrera elektronikoa: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4621776/ https://ncbi.nlm.nih.gov/pubmed/26496101 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/TA.0000000000000837 |
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