C-reactive protein binding to FcγRIIa on human monocytes and neutrophils is allele-specific

C-reactive protein (CRP) is involved in host defense, regulation of inflammation, and modulation of autoimmune disease. Although the presence of receptors for CRP on phagocytes has been inferred for years, their identity was determined only recently. FcγRIa, the high-affinity IgG receptor, binds CRP...

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Publicado en:J Clin Invest
Autores principales: Stein, Mary-Pat, Edberg, Jeffrey C., Kimberly, Robert P., Mangan, Erin K., Bharadwaj, Dwaipayan, Mold, Carolyn, Du Clos, Terry W.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Clinical Investigation 2000
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Article
Acceso en línea:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC377443/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10675363/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI7817
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