MD Simulations and FRET Reveal an Environment-Sensitive Conformational Plasticity of Importin-β

The nuclear pore complex mediates nucleocytoplasmic transport of macromolecules in eukaryotic cells. Transport through the pore is restricted by a hydrophobic selectivity filter comprising disordered phenylalanine-glycine-rich repeats of nuclear pore proteins. Exchange through the pore requires spec...

Полное описание

Сохранить в:
Библиографические подробности
Опубликовано в: :Biophys J
Главные авторы: Halder, Kangkan, Dölker, Nicole, Van, Qui, Gregor, Ingo, Dickmanns, Achim, Baade, Imke, Kehlenbach, Ralph H., Ficner, Ralf, Enderlein, Jörg, Grubmüller, Helmut, Neumann, Heinz
Формат: Artigo
Язык:Inglês
Опубликовано: The Biophysical Society 2015
Предметы:
Channels and Transporters
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4621615/
https://ncbi.nlm.nih.gov/pubmed/26200863
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2015.06.014
Метки: Добавить метку
Нет меток, Требуется 1-ая метка записи!

Схожие документы