Associations of prodynorphin sequence variation with alcohol dependence and related traits are phenotype-specific and sex-dependent

We previously demonstrated that prodynorphin (PDYN) haplotypes and single nucleotide polymorphism (SNP) rs2281285 are associated with alcohol dependence and the propensity to drink in negative emotional states, and recent studies suggest that PDYN gene effects on substance dependence risk may be sex...

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Publicado en:Sci Rep
Autores principales: Winham, Stacey J., Preuss, Ulrich W., Geske, Jennifer R., Zill, Peter, Heit, John A., Bakalkin, Georgy, Biernacka, Joanna M., Karpyak, Victor M.
Formato: Artigo
Lenguaje:Inglês
Publicado: Nature Publishing Group 2015
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4621530/
https://ncbi.nlm.nih.gov/pubmed/26502829
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep15670
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