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Associations of prodynorphin sequence variation with alcohol dependence and related traits are phenotype-specific and sex-dependent

We previously demonstrated that prodynorphin (PDYN) haplotypes and single nucleotide polymorphism (SNP) rs2281285 are associated with alcohol dependence and the propensity to drink in negative emotional states, and recent studies suggest that PDYN gene effects on substance dependence risk may be sex...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Winham, Stacey J., Preuss, Ulrich W., Geske, Jennifer R., Zill, Peter, Heit, John A., Bakalkin, Georgy, Biernacka, Joanna M., Karpyak, Victor M.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2015
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4621530/
https://ncbi.nlm.nih.gov/pubmed/26502829
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep15670
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