Associations of prodynorphin sequence variation with alcohol dependence and related traits are phenotype-specific and sex-dependent

We previously demonstrated that prodynorphin (PDYN) haplotypes and single nucleotide polymorphism (SNP) rs2281285 are associated with alcohol dependence and the propensity to drink in negative emotional states, and recent studies suggest that PDYN gene effects on substance dependence risk may be sex...

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Udgivet i:Sci Rep
Main Authors: Winham, Stacey J., Preuss, Ulrich W., Geske, Jennifer R., Zill, Peter, Heit, John A., Bakalkin, Georgy, Biernacka, Joanna M., Karpyak, Victor M.
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 2015
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4621530/
https://ncbi.nlm.nih.gov/pubmed/26502829
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep15670
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